The American retreat from the Middle East signals weakness, and encourages an Iranian quest for regional hegemony that was bolstered by the P5+1 nuclear deal. The most dangerous consequence of current American foreign policy in the region is the likelihood of nuclear proliferation. Moreover, the current American approach allows for Russian encroachment in the region, which enhances the power of the radical axis led by Iran. It also opens the way for the ‘Finlandization’ of the Gulf and the Caspian basin by Iran. US weakness in the Middle East inevitably will have ripple effects in other parts of the globe.