In its early years, the State of Israel made major investments in science and technology in alignment with its national security strategy of establishing a qualitative advantage over its adversaries. This initiative positioned Israel's defense sector as the driving force behind its technological progress. Over time, Israel's focus has shifted toward civilian-commercial technology, earning it the nickname “Start-Up Nation”. Upon examining the unique continuing dynamics between Israel’s thriving commercial hi-tech sector and its defense sector, it becomes evident that Israel's security situation remains the fuel that powers the country’s bustling start-up ecosystem.