Azerbaijan, a Shia Muslim-majority country, has the longest-standing and most comprehensive partnership with Israel. Azerbaijan is the only strategic partner in the Muslim world of the US’s main ally in the Middle East. It shares borders with both Iran and Russia, and may thus be considered one of the pillars of Israel’s regional strategic security architecture. Against the backdrop of the Trump administration’s efforts to reshape the global order, Azerbaijan’s significance—for both American and Israeli strategic interests—has grown even further. This is driven by key trends in Washington’s new foreign policy approach, within which Azerbaijan’s advantages and capabilities can be effectively leveraged.